Detection of internal body time bt via a few time point assay has been a longstanding challenge in medicine because bt information can be exploited to maximize potency and minimize toxicity during drug administration and thus will enable highly optimized medication. Metabolomics based measurement of bt is performed as described for expression based measurement of bt except that 2 samples are used for an estimation of bt. In the metabolite timetable method we used 2 samples with 12 h sampling time interval eg zt0 and zt12 are used for 1 measurement of bt to calibrate measurement to measurement experimental fluctuations of detection sensitivity which usually differs among metabolites. Metabolomics based measurement of bt is performed as described for expression based measurement of bt except that 2 samples are used for an estimation of bt. Similarly in the molecular timetable method one can measure the bt of the day by profiling the up and down patterns of substances in the molecular timetable. Similarly in the molecular timetable method one can measure the bt of the day by profiling the up and down patterns of substances in the molecular timetable.
Estimate the time of the day by watching the opening and closing pattern of various flowers. Estimate the time of the day by watching the opening and closing pattern of various flowers. In the metabolite timetable method we used 2 samples with 12 h sampling time interval eg zt0 and zt12 are used for 1 measurement of bt to calibrate measurement to measurement experimental fluctuations of detection sensitivity which usually differs among metabolites. Title measurement of internal body time by blood metabolomics abstract detection of internal body time bt via a few time point assay has been a longstanding challenge in medicine because bt information can be exploited to maximize potency and minimize toxicity during drug administration and thus will enable highly optimized medication. To make this method clinically feasible we now performed blood metabo. To make this method clinically feasible we now performed blood metabo.